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Glutathione Articles - HIV

  1. Wu G, Fang Y, Yang S, Lupton JR, and Turner ND. Glutathione metabolism and its implications for health. J. Nutr. 2004; 134: 489–492.

  2. Aukrust P, Muller F, Svardal AM, Ueland T, Berge RK, and Frøland SS. Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus–infected patients during highly active antiretroviral therapy—potential immunomodulatory effects of antioxidants. The Journal of Infectious Diseases 2003; 188:232–8.

  3. Mialocq P, Oiry J, Puy JY, Rimaniol AC, Imbach JL, Dormont D, Clayette P. Oxidative metabolism of HIV-infected macrophages: the role of glutathione and a pharmacologic approach. Pathol Biol (Paris). 2001 Sep;49(7):567-71.

  4. Sung JH, Shin SA, Park HK, Montelaro RC, Chong YH. Protective effect of glutathione in HIV-1 lytic peptide 1-induced cell death in human neuronal cells. J Neurovirol. 2001 Oct;7(5):454-65.

  5. Trotti R, Rondanelli M, Anesi A, Gabanti E, Brustia R, Minoli L. Increased erythrocyte glutathione peroxidase activity and serum tumor necrosis factor-alpha in HIV-infected patients: Relationship to on-going prothrombotic state. J Hematother Stem Cell Res. 2002 Apr;11(2):369-75.

  6. Price TO, Ercal N, Nakaoke R, Banks WA. HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. Brain Res. 2005 May 31;1045(1-2):57-63. Epub 2005 Apr 19.

  7. Ghezzi P, Romines B, Fratelli M, Eberini I, Gianazza E, Casagrande S, Laragione T, Mengozzi M, Herzenberg LA, and Herzenberg LA. Protein glutathionylation: Coupling and uncoupling of glutathione to protein thiol groups in lymphocytes under oxidative stress and HIV infection. Molecular Immunology. 2001; 38: 773–780.

  8. De Rosa SC, Zaretsky MD, Dubs JD, Roederer M, Anderson M, Green A, Mitra D, Watanabe N, Nakamura H, Tjioe I, Deresinski SC, Moore WA, Ela SW, Parks D, Herzenberg LA, and Herzenberg LA. N-acetylcysteine replenishes glutathione in HIV infection. European Journal of Clinical Investigation 2000; 30:915-929.

  9. Diaz PT, Wewers MD, King M, Wade J, Hart J and Clanton TL. Regional differences in emphysema scores and BAL glutathione levels in HIV-infected individuals. Chest 2004;126:1439-1442.

  10. Sbrana E, Paladini A, Bramanti E, Spinetti MC, Raspi G. Quantitation of reduced glutathione and cysteine in human immunodeficiency virus-infected patients. Electrophoresis. 2004 Jun;25(10-11):1522-9.

  11. Droge W and Holm E. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. FASEBJ. 1997; 11:1077-1089.

  12. Townsend DM, Tew KD, Tapiero H. The importance of glutathione in human disease. Biomed Pharmacother. 2003 May-Jun;57(3-4):145-55.

  13. Herzenberg LA, DeRosa SC, Dubs JG, Roederer M, Anderson MT, Ela SW, Deresinski SC, Herzenberg LA. Glutathione deficiency is associated with impaired survival in HIV disease. Proc Natl Acad Sci. USA Vol. 94, pp1967–1972, March 1997.

  14. Kline Erik R, Kleinhenz Dean J, Liang Bill, Dikalov Sergey, Guidot David M, Hart Michael C, Jones Dean P, Sutliff Roy L. Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration. Am J Physiol Heart Circ Physiol. 2008 June ; 294(6): H2792–H2804.


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