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Glutathione FAQs

  How is Glutathione shipped and stored?
  What is Glutathione derived from?
  How do I find a doctor in my area that will write a prescription and administer it?
  Is Glutathione FDA approved?
  What is Glutathione?
  What study proves it works?
  What improvement in symptoms can one expect?
  How long can a person take Glutathione and how long will the effect last after I stop using it?
  How long has Glutathione been used?
  How is Glutathione given?
  How to administer injectable Glutathione?
  How does a doctor or patient find out more information about Glutathione and how to administer it?
  How do you measure Glutathione levels?
  How can I get Glutathione?
  What makes Wellness Glutathione better than any other?
  What about side effects of the drug and interactions with other drugs?
  How does the Glutathione work?
  Will my insurance cover it?


How is Glutathione shipped and stored?

Glutathione is shipped overnight with an ice brick in a cooler. The order, once shipped, is usually delivered by 12 noon the following day (Mon-Thurs) by Federal Express. Please allow up to 24 hours for your order to be processed. The glutathione should be kept in the refrigerator and protected from light after received and until given to the patient.

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What is Glutathione derived from?

Glutathione is made like many other bio-engineered products, by feeding a micro-organism a certain nutrient and allowing it to make the glutathione.

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How do I find a doctor in my area that will write a prescription and administer it?

Wellness has a list of doctors all over the country who have allowed us to refer them patients. If we do not have a doctor on the list in your area we will be glad to try to find one in your area. If doctors want to be on our list please have them call and we will be happy to add them.

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Is Glutathione FDA approved?

No compounded product is FDA approved in the narrow sense of the definition, but Glutathione is in the GRAS (generally regarded as safe) category.

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What is Glutathione?

It is an important chemical that acts as a powerful antioxidant to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. It also acts to recycle vitamin C & E which also reduce free radicals.  Click here for a more detailed information about "What is Glutathione/GSH?"

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What study proves it works?

The landmark study was done by the Department of Neurology, University of Sassari, Italy in 1996. In this study all patients improved significantly after glutathione therapy with a 42% decline in disability.

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What improvement in symptoms can one expect?

Many patients have had profound improvements with respect to reduction of rigidity, increased mobility, improved ability to speak, less depression, and decreased tremor. Glutathione has the added benefit of protecting the brain from free radical damage, thus possibly slowing the progression of the underlying illness.

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How long can a person take Glutathione and how long will the effect last after I stop using it?

It can be taken permanently. In the 1996 Italian study the therapeutic effect lasted 2-4 months after therapy was stopped.

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How long has Glutathione been used?

Dr. David Perlmutter, a board certified neurologist from Naples, Florida, started using it in 1998 for his Parkinson's patients. Today thousands of patients have benefited from the use of Glutathione.

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How is Glutathione given?

It is given intravenously in the arm by IV push over 10 to 15 minutes usually three times a week in a physician's office.

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How to administer injectable Glutathione?

Wellness uses liquid glutathione, not reconstituted powder. L-Glutathione is produced by direct fermentation whereby the base media is a molasses based sugar. A qualified healthcare practitioner should administer it, at least initially, as follows:

1. Dilute the appropriate dosage of glutathione liquid in 10cc of sterile normal saline. Usually vial contains 200mg/ml, but read the label.
2. This solution is then injected through a 23-gauge butterfly catheter intravenously over a 15 to 20 minute period of time.
3. Alternatively, many patients choose to have intravenous access ports inserted. This allows frequent glutathione administration without repeated needle
    sticks.
4. IV's can begin at 3 times a week and may be increased to daily injections based on physician recommendation.

Glutathione must be stored in a refrigerator in a foil bag to protect from light. The expiration date is 6 months.

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How does a doctor or patient find out more information about Glutathione and how to administer it?

A book, BrainRecovery.com, and an instructional video by Dr. Perlmutter is available from Wellness Pharmacy«.

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How do you measure Glutathione levels?

Oxidative stress causes a deficiency of intracellular glutathione, therefore making it difficult to measure. Most practitioners will order an oxidative stress panel or amino acid analysis to look at the amino acids that make up glutathione or are involved with the synthesis of glutathione. You can also measure total glutathione and look at the ratio of reduced glutathione to oxidized glutathione to assess glutathione levels. Several labs currently have these oxidative stress or amino acid test kits. All require a prescription. Doctor's Data and Genova Diagnostics are excellent resources for labs.

It can be tough to measure reduced glutathione in Red Blood Cells because of the quick turnover. You want to measure total glutathione levels and looking at the reduced/oxidized ratios and there are tests available that do that from Genova Diagnostics.

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How can I get Glutathione?

Essential GSH is available without a prescription on the Wellness Pharmacy site. > Buy Essential GSH

For other forms of Glutathione you must have a prescription from a licensed doctor. The prescription can be called or faxed in to Wellness Pharmacy«.

Fax: 1-800-369-00302
Phone: 1-800-227-2627

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What makes Wellness Glutathione better than any other?

Wellness has developed a patented method of preparation that enhances glutathione's stability which delivers it in a near 100% reduced form. This assures that the glutathione is as potent and effective as it can be. Dr Perlmutter's book, BrainRecovery.com, references Wellness as his sole source for injectable glutathione.

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What about side effects of the drug and interactions with other drugs?

There are no significant side effects with glutathione. It is not recommend to be given at the same time as any other IV products. For example, vitamin C can oxidize it and render it ineffective if given along with it. It is contraindicated to give glutathione while a person is taking cancer chemotherapy drugs since glutathione increases the ability of the liver to process chemicals. This may cause the chemotherapy to be less effective.

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How does the Glutathione work?

There are many factors that explain why glutathione is so beneficial in Parkinson's disease. First, glutathione has the unique ability to make certain areas of the brain more sensitive to dopamine, so that even though dopamine is decreased, it nevertheless becomes more effective - aka it increases the dopamine receptor's sensitivity. Another possible mechanism is its antioxidant activity-protecting the brain from free radical damage. Additionally, glutathione has tremendous detoxifying ability through out the entire body.

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Will my insurance cover it?

It depends on the insurance company. Many of them do cover it. Wellness will send insurance information with your order, if requested, so you can file and get reimbursed. We will also be glad to assist you in filling out your insurance forms if you forward them to us. We value your business and will help you in any way we can.

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