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home > articles > diabetes > glutathione in overweight patients with poorly controlled type 2 diabetes Glutathione Articles - Diabetes
Glutathione in overweight
patients with poorly controlled type 2 diabetes ABSTRACT Increased lipid peroxidation due
to an altered intracellular ratio between free radicals and antioxidant
systems has been associated with development of diabetic complications. This
report explores the biochemical reliability of this hypothesis by measuring
glutathione (GSH) in overweight patients with poorly controlled type 2
diabetes. GSH, a crucial antioxidant and cofactor for the selenium-dependent
glutathione peroxidase (GSHPx), was analyzed
in red blood cells. Ten overweight and poorly controlled type 2 diabetic
patients (6 women and 4 men, age 45 -60 years, body mass index (BMI) 26 -32
kg/m2, HbA1c > 9.4%) and 13 healthy normal weight controls (7 women and 6
men, age 40-60 years, BMI 20-25 kg/m2, HbA1c <6.0 %) were included in the
study. The > download PDF version of this abstract If you would like us to send you the full text version of the article listed above, please contact us by phone or e-mail: Caron Coats
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