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Glutathione Articles - ASD (Autism Spectrum Disorders)
Glutathione in the treatment of autism: a preliminary
investigation
Leigh Ann Chapman ND, Will Gregory PhD,
Heather Zwickey PhD
Epub ahead of print
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BACKGROUND:Evidence suggests
that autism spectrum disorders are influenced by the intricate interface
between genetics, immune function, toxic environmental exposures, and
increased oxidative stress. Glutathione (GSH) serves as a potent immune
system activator and one of the human body’s most powerful antioxidants,
providing cellular protection from the damage of free radicals. This
case series builds upon anecdotal evidence that oral glutathione
supplementation increases autistic patients’ blood GSH levels as well as
improves clinical parameters in areas such as communication,
sociability, cognitive awareness and physical symptoms.
OBJECTIVE: To review cases of patients treated with oral glutathione
supplementation, Essential GSH, during the course of biomedical
treatment of autism spectrum disorder and document changes in blood GSH
levels as well as symptoms of autism using the Autism Treatment
Evaluation Checklist (ATEC).
METHODS: Seven children with a diagnosis of an Autism spectrum disorder
are assigned to receive daily supplementation with an oral liposomal
glutathione replacement in addition to customary biomedical treatment.
Whole blood glutathione was tested at baseline, three weeks and six
weeks of treatment. Behavioral, cognitive, social and physical symptoms
were monitored at the same intervals using the Autism Treatment
Evaluation Checklist (ATEC.)
RESULTS: The increase of whole blood glutathione levels as well as
improvement in behavior and physical symptoms of children with autism
was statistically significant after oral liposomal glutathione,
Essential GSH, replacement therapy.
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