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Glutathione Articles - Acetaminophen Toxicity

1. Marzullo L. An update of N-acetylcysteine treatment for acute acetaminophen toxicity in children. Curr Opin Pediatr. 2005 Apr;17(2):239-45.

2. Riordan SM and Williams R. Alcohol exposure and paracetamol-induced hepatotoxicity. Addict Biol. 2002 Apr;7(2):191-206.

3. Spielberg SP. Acetaminophen toxicity in lymphocytes heterozygous for glutathione synthetase deficiency. Can J Physiol Pharmacol. 1985 May;63(5):468-71.

4. Zimmerman HJ and Maddrey WC. Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure. Hepatology. 1995 Sep;22(3):767-73. Erratum in: Hepatology 1995 Dec;22(6):1898.

5. James LP, Mayeux PR and Hinson JA. Acetaminophen-induced hepatotoxicity. Drug Metabolism and Disposition. 2003;31:1499-1506.

6. Lauterburg BH. Analgesics and glutathione. Am J Ther. 2002 May-Jun;9(3):225-33.

7. Bajt ML, Knight TR, Lemasters JJ and Jaeschke H. Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: Protection by n-acetyl cysteine. Toxicological Sciences. 2004;80:343-349.

8. Duggin GG. Combination analgesic-induced kidney disease: The Australian experience. Am J Kidney Dis. 1996 Jul;28(1 Suppl 1):S39-47.

9. Slitt AM, Dominick PK, Roberts JC and Cohen SD. Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion. Basic Clin Pharmacol Toxicol. 2005 Jun;96(6):487-94.

10. Berkeley LI, Cohen JF, Crankshaw DL, Shirota FN and Nagasawa HT. Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydrylmodified prodrug of glutathione. J Biochem Mol Toxicol. 2003;17(2):95-7.

11. Larsen LC and Fuller SH. Management of acetaminophen toxicity. American Family Physician. January 1996.

12. Vendemiale G, Grattagliano I, Altomare E, Turturro N and Guerrieri F. Effect of acetaminophen administration glutathione compartmentation energy metabolism in the rat.  Biochem Pharmacol. 1996 Oct 25;52(8):1147-54.

13. Greabu M and Olinescu R. The formation of oxidative stress condition in the experimental chemically induced hepatotoxicity. Rocz Akad Med Bialymst. 2002;47:86-94.

14. Jaeschke H, Knight TR and Bajt ML. The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity. Toxicol Lett. 2003 Oct 15;144(3):279-88.

15. Oak S and Choi BH. The effects of glutathione glycoside in acetaminopheninduced liver cell necrosis. Exp Mol Pathol. 1998;65(1):15-24.

16. Wu J, Danielsson A and Zern MA. Toxicity of hepatotoxins: New insights into mechanisms and therapy. Expert Opin Investig Drugs. 1999 May;8(5):585-607.

17. Prescott LF and Critchley JA. The treatment of acetaminophen poisoning. Annu Rev Pharmacol Toxicol. 1983;23:87-101.

18. Salgia AD and Kosnik SD. When acetaminophen use becomes toxic: Treating acute accidental and intentional overdose. Postgrad Med. 1999 Apr;105(4):81-4, 87, 90.

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